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pentobarbital will reduce the level or effect of buprenorphine, long-acting injection by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. People who transfer to buprenorphine extended-acting injection from transmucosal buprenorphine coadministered with CYP3A4 inducers ought to be monitored to ensure buprenorph